Evaluation of choroidal vascular index in vitamin D deficiency

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Akmaz O., Guven Y. Z., Gumus F., Karatas M., Yilmaz R. S., DEMİR İ., ...Daha Fazla

Retina-Vitreus, cilt.33, sa.3, ss.167-173, 2024 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 3
  • Basım Tarihi: 2024
  • Doi Numarası: 10.37845/ret.vit.2024.33.27
  • Dergi Adı: Retina-Vitreus
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.167-173
  • Anahtar Kelimeler: Choroidal thickness, choroidal vascular index, luminal area, stromal area, vitamin D
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Purpose: The goal of this study is to investigate the effects of vitamin D deficiency in choroidal vacular index (CVI) and choroidal thickness (CT) of the subfoveal and peripapillary area. Materials and Methods: All macular and peripapillary images were taken by enhanced depth imaging (EDI) mode of spectral domain optical coherence tomography (SD-OCT). The CT was measured at five different points; at the subfovea and at 500μm intervals away from the optic nerve in the superior, inferior, nasal, and temporal quadrants. Choroid images taken from subfoveal and peripapillary region were divided into luminal and stromal areas determined by image binarization method. CVI was defined as the ratio of LA to total choroid area (TCA). Results: The mean vitamin D levels were 10.58±3.04 ng/mL in Group 1, and 24.92±3.77 ng/mL in Group 2 (p <0.0001). Subfoveal and peripapillary nasal, superior and inferior CT was found to be statistically significantly thinner in Group 1 (p <0.001, all). CVI in subfoveal region, peripapillary nasal and superior quadrants was statistically significantly lower in Group 1 (p=0.001, p=0.012, p=0.011, respectively). There were positive correlations between vitamin D levels and subfoveal CT, nasal, superior, and inferior peripapillary CT (p < 0.001, p = 0.001, p < 0.001, p < 0.001, respectively) and subfoveal CVI, nasal, and superior peripapillary CVI (p = 0.007, p = 0.007, p = 0.003 respectively). Conclusion: In individuals with vitamin D deficiency, both CT and CVI may be negatively affected in the subfoveal, peripapillary nasal and superior quadrants..