The effects of dexmedetomidine administered at two different times on postoperative shivering İki farkli zamanda uygulanan deksmedetomidinin ameliyat sonrasi titreme üzerine etkisi
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.34, sa.5, ss.320-326, 2006 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 34 Sayı: 5
- Basım Tarihi: 2006
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.320-326
- Anahtar Kelimeler: Dexmedetomidine, General anesthesia, Postoperative shivering
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Aim: We aimed to investigate the hypothesis that infusion of dexmedetomidine at the beginning or at the end of the operation could change the efficacy of the drug in preventing postoperative shivering. Material and Methods: 60 ASA I-II physical status patients undergoing total abdominal hysterectomy and bilateral salpingo-oopherectomy or myomectomy arc randomly allocated into three groups. Dexmedetomidine 1 μg h-1 is infused in 5 minutes just after intubation (group 1) or at the end of the surgery (group 2). Patients in group 3 did no receive dexmedetomidinc infusion. Nasopharyngeal temperature levels, the time from termination of desfluranc application until extubation, the presence of shivering, Ramsay sedation score, modified Aldrete score, verbal pain score, the consumption of analgesics and the presence of nausea were recorded. Results: In group 1 and group 2, the incidence of shivering was lower than group 3 (p<0.001). In group 2, shivering incidence was lower than group 1 (p<0.05). In group 2, extubation time was longer than the other groups (p<0.05). Sedation scores at 15, 30 and 45 minutes postoperatively were higher than the other groups (p<0.001). In group 1 (p<0.05) and group 2 (p<0.01), verbal pain score at 60 minutes postopcratively was lower than group 3. The consumption of analgesics was lower in group 2 when compared with group 3 (p<0.01). The incidence of nausea was lower in group 2 when compared with group 3 (p<0.05). Conclusion: Although the administration of dexmedetomidine after intubation or at the end of surgery reduced the incidence of shivering, the late application was more effective when compared with early administration. In addition to better analgesia level, late administration of dexmedetomidine prevented nausea. But as this application can elongate extubation time and cause sedation during 45 minutes postoperatively, close observation of these patients is necessary.