Breakthroughs in the Health Effects of Plant Food Bioactives: A Perspective on Microbiomics, Nutri(epi)genomics, and Metabolomics
Journal of Agricultural and Food Chemistry, cilt.66, sa.41, ss.10686-10692, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 66 Sayı: 41
- Basım Tarihi: 2018
- Doi Numarası: 10.1021/acs.jafc.8b03385
- Dergi Adı: Journal of Agricultural and Food Chemistry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.10686-10692
- Anahtar Kelimeler: phytochemicals, interindividual variability, personalized nutrition, metabolome, gut microbiota
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Plant bioactive compounds consumed as part of our diet are able to influence human health. They include secondary metabolites like (poly)phenols, carotenoids, glucosinolates, alkaloids, and terpenes. Although much knowledge has been gained, there is still need for studies unravelling the effects of plant bioactives on cardiometabolic health at the individual level, using cutting-edge high-resolution and data-rich holistic approaches. The aim of this Perspective is to review the prospects of microbiomics, nutrigenomics and nutriepigenomics, and metabolomics to assess the response to plant bioactive consumption while considering interindividual variability. Insights for future research in the field toward personalized nutrition are discussed.