The effects of antihypertensive drugs on intraoperative hemodynamics in noncardiac surgery Nonkardiyak Cerrahide Antihipertansif Ilaçlarin Intraoperatif Hemodinami Üzerine Etkileri

Aytekin H., Aytekin A., EKİNCİ O., Özgültektn A.

Gogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisi, cilt.22, sa.4, ss.161-167, 2016 (Scopus)

Özet

Objective: Antihypertensive drugs have effects on hemodynamics during anesthesia. We aimed to compare the effects of antihypertensive drugs and medication withdrawal time on intraoperative hemodynamics in our study. Material and Method: Patients using antihypertensive drugs who were admitted to anesthesiology clinic were taken into the study by taking hospital approval and written informed consent. Antihypertensive drugs used by ASA l-lll patients aged 18-75 years who underwent elective abdominal operation, withdrawal time and intraoperative hemodynamics were recorded. Frequently used angiotensin converting enzyme inhibitors (ACEl), calcium channel blockers (CCD) and angiotensin receptor blockers (ARB) are divided into 3 groups asACEI or ARB (group l)y CCB (group 2) and ACEl + CCB or ARB + CCB (group 3). According to time of drug withdrawal, groups were divided into two subgroups: 24 hours before and the morning of operation. 124 of the 156 patients were taken into the study. 32 patients were excluded due to the inconvenience of using compulsory medication or withdrawal time. There was no significant difference in demographic data between the groups (p>0.05). There was no significant difference between ACEl or ARB group and CCB group in mean arterial pressures service, before induction, intraoperatively and after extubation (p>0.05). There was a significant difference in mean arterial pressures between these two groups and ACEl + CCB or ARB + CCB group, which was significantly lower in the ARB + CCB group (p