Recurrent vasculopathic skin lesions associated with homozygous protein C deficiency
Pediatric Dermatology, cilt.24, sa.1, ss.57-60, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 24 Sayı: 1
- Basım Tarihi: 2007
- Doi Numarası: 10.1111/j.1525-1470.2007.00335.x
- Dergi Adı: Pediatric Dermatology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.57-60
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Symptomatic protein C deficiency is a rare condition. Vasculopathy associated with hypercoagulable state in protein C deficiency has also been reported rarely. We described a boy who was diagnosed as having homozygous protein C deficiency during the neonatal period, when he developed purpura fulminans. At 7 years of age, he developed recurrent, painful, nonscarring, purpuric skin lesions. Histopathologic skin findings were compatible with those of vasculopathy. The histopathologic characteristics of these vasculopathic lesions and the pathogenetic mechanisms of their association with protein C deficiency are discussed. © 2007 The Authors.