The role of active breathing control-moderate deep inspiration breath-hold (ABC-mDIBH) usage in non-mastectomized left-sided breast cancer radiotherapy: A dosimetric evaluation Non-mastektomize sol meme kanseri radyoterapisinde aktif nefes kontrolü-orta derin i̇nspirasyonda nefes tutma kullanımının rolü: Dozimetrik bir deǧerlendirme
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi, cilt.22, sa.3, ss.147-155, 2012 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 3
- Basım Tarihi: 2012
- Doi Numarası: 10.4999/uhod.11075
- Dergi Adı: UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.147-155
- Anahtar Kelimeler: Breast cancer, Breast-conserving surgery, Radiotherapy, Active breathing control, Breath-hold
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The aim of this study is to evaluate the dosimetric impact of utilizing Active Breathing Control-moderate deep inspiration breath-hold (ABC-mDIBH) technique in early-stage left-sided breast cancer radiotherapy (RT). Twenty-five patients with left-sided early-stage breast cancer undergoing breast-conserving surgery referred to our department for adjuvant radiotherapy between October 2010 and October 2011 were scanned with computed tomography (CT)-simulator at free breathing (FB) and ABC-mDIBH for radiation treatment planning. Two separate treatment plans were generated for each patient, with and without ABC-mDIBH to comparatively evaluate dose-volume parameters of both plans. Dose-volume parameters of lung, heart, left anterior descending artery (LAD), contralateral breast and spinal cord were significantly reduced with ABC-mDIBH compared to free breathing (p< 0.001). The use of ABC-mDIBH technique in the practice of early-stage left-sided breast cancer radiotherapy improves critical organ sparing with the dosimetrically-confirmed potential to decrease treatment-related morbidity and mortality. This respiratory management strategy is a promising tool that may be routinely used for the treatment of patients with early-stage left-sided breast cancer.