Late type vitamin K deficiency related with prolonged antibiotic therapy in a 7-month-old infant
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi, cilt.20, sa.2, ss.106-109, 2010 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 2
- Basım Tarihi: 2010
- Dergi Adı: UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.106-109
- Anahtar Kelimeler: Intracranial hemorrhage, Vitamin K deficiency, Antibiotic therapy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We herein report a case of intracranial hemorrhage due to late-type vitamin K deficiency during antibiotic therapy. A 7-month-old male infant was hospitalized for convulsion. He was diagnosed as bacterial meningitis, and treatment with ceftriaxone and vancomycine was administered. On the 16th day of therapy, a subdural hemorrhage occurred. Protrombin time and partial thromboplastin time were found to be prolonged. Platelet count, fibrinogen and D-Dimer levels were all normal. The patient was diagnosed as Vitamin K Deficiency Bleeding. He was treated with 3 mg vitamin K intravenously and the subdural hematoma was drained. His follow up was uneventful. We suggest that patients especially who receive antibiotic treatment for more than two weeks should be followed for late-type vitamin K deficiency.