The prognostic value of fQRSTa in patients with aortic stenosis undergoing surgical aortic valve replacement
Journal of Cardiac Surgery, cilt.35, sa.10, ss.2627-2632, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 10
- Basım Tarihi: 2020
- Doi Numarası: 10.1111/jocs.14858
- Dergi Adı: Journal of Cardiac Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
- Sayfa Sayıları: ss.2627-2632
- Anahtar Kelimeler: cardiovascular research, valve repair, replacement
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Surgical aortic valve replacement (sAVR) is the ultimate therapy for severe aortic stenosis (AS) in suitable patients. Prognostic factors of sAVR are great interest in recent studies. Frontal QRS-T angle (fQRSTa) is a novel marker of ventricular repolarization abnormalities. In this study, we aimed to investigate the prognostic value of fQRSTa in patients with severe symptomatic AS undergoing sAVR. Methods: A total of 372 patients with severe degenerative AS who underwent successful sAVR were included in this retrospective study. Then, patients were divided into two groups: patients with narrow fQRSTa (≤90°) as group 1 and wide fQRSTa (>90°) as group 2. Perioperative and postoperative clinical evaluation and time of death were recorded from all subjects. Results: The incidence of total mortality was higher in patients with wider fQRSTa (13.8% [15]; 4.9% [9], P =.013) compared to patients with narrow fQRSTa. In multivariate logistic regression analysis, advanced age (odds ratio [OR] = 1.054; 95% confidence interval [CI] = 1.004-1.106; P =.034), dyspnea (OR = 7.687; 95% CI = 2.296-25.729; P =.001), lower efection fraction (OR = 0.924; 95% CI = 0.884-0.966; P =.001), in-hospital duration (OR = 1.051; 95% CI = 1.016-1.088; P =.004) and wider fQRSTa (OR = 4.029; 95% CI = 1.383-11.740; P =.011) were found to be independent predictors of mortality. Additionally, a Kaplan-Meier survival analysis also revealed that long-term survival was found to be significantly decreased in patients with wider fQRSTa (log-rank P =.014). Conclusion: fQRSTa was related with poor prognosis in patients with AS undergoing sAVR. fQRSTa was also an independent predictor of mortality in this population.