Evaluation of clinical and demographic data of children with chronic spontaneous urticaria in Antalya province Antalya il merkezinde kronik spontan ürtikeri olan çocukların klinik ve demografik verilerinin değerlendirilmesi
Pamukkale Medical Journal, cilt.13, sa.1, ss.129-135, 2020 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 1
- Basım Tarihi: 2020
- Doi Numarası: 10.31362/patd.581096
- Dergi Adı: Pamukkale Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.129-135
- Anahtar Kelimeler: autoimmune thyroiditis, childhood, Chronic urticaria, urticaria activity scoring, urticaria control test
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: The aim of the study was to investigate the etiology of chronic urticaria in children and the related clinical and laboratory findings in our city. Materials and methods: One hundred-seven patients aged between 7-17 years who were diagnosed with chronic spontaneous urticaria (CSU) in our clinic were retrospectively reviewed. Demographic and clinical characteristics, laboratory findings, atopy, infection, and autoimmunity tests of patients with CSU were evaluated. In addition, Urticaria Activity Score (UAS) and Urticaria Control Test (UCT) were applied to evaluate disease severity. Results: A total of 107 patients with a mean age of 11.99±3.34 were enrolled in the study. Angioedema was associated with 66% of the patients. The median duration of urticaria was 8 (2-72) months. Allergic diseases were associated with 36% of the patients. Twelve percent of patients had asthma and 21% had allergic rhinitis. Inhaler sensitivity was detected in 33% of cases and food allergen sensitivity in 6.5% of cases. Antinuclear antibody (ANA) levels were positive in 16.8% of the patients with CSU and 6.5% of the children had positive thyroid autoantibody. Urinary tract infection was found in 3% of the patients.1.9% of the patients with CSU were positive for helicobacter pylori and 1.9% of the patients had positive stool examination results for parasites. The mean UAS7 was 12.96±9.8 and the mean UCT was 8.43±2.8. No significant difference was found between the groups in terms of age, gender, presence of angioedema, duration of disease and ANA positivity when compared with control (n=24) and uncontrolled (n=83) patients (respectively, p=0.842, p=0.646, p=0.347, p=0.590, p=0.316). Conclusion: In children, atopic diseases, infections, parasitic infestations are present in the etiology of CSU, whereas in most cases the diagnosis remains idiopathic.