Diagnostic Conflict in Occult Breast Cancers and Clinical Results of a Tertiary Center: A Cross-sectional Study
Indian Journal of Surgery, cilt.85, sa.3, ss.522-530, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 85 Sayı: 3
- Basım Tarihi: 2023
- Doi Numarası: 10.1007/s12262-022-03510-4
- Dergi Adı: Indian Journal of Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, Veterinary Science Database
- Sayfa Sayıları: ss.522-530
- Anahtar Kelimeler: Occult, Origin, Ectopic, Radiotherapy, Breast, Cancer
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Our aim is to present the results of early-stage clinicopathological occult breast cancer cases in a tertiary centre for breast diseases. There were 17 cases (T0/TxN 1,2,3 M0/M1) that were classified as clinicoradiological occult breast cancer (crOBC) from 01 January 2006 to 01 January 2018. By re-evaluating the postoperative histopathological and immunohistochemical results, the patients were divided into three groups; early-stage clinicopathological occult breast cancer [ecpOBC (T0/TxN1,2,3M0)], metastatic clinicopathological occult breast cancer [(mcpOBC (T0/TXN + M1)], and non-occult breast cancer (nOBC). Patients with ecpOBC (n = 11) were included in the study. The frequency of operable ecpOBC was 0.46% (11/2342) and the frequency of non-operable mcpOBC was 0.08% (2/2342). While modified radical mastectomy (MRM) was performed on 27.3 (3/11) of the patients, 72.7% (8/11) had axillary lymph node dissection (ALND). The operated MRM and ALND groups were followed up for at least 3 years after receiving chemotherapy (CTX) and radiotherapy (RT). The 3-year disease-free survival (DFS) rates of the groups were respectively 100% and 87.5%, and there was no significant difference between the groups regarding DFS (p = 0.540). Considering the concern for cosmesis in ecpOBC patients, ALND seems to be as an appropriate surgical approach.