Mediterranean spotted fever: Report of two cases Akdeniz benekli ateşi: İki olgu sunumu
Turkiye Klinikleri Journal of Medical Sciences, cilt.31, sa.6, ss.1554-1558, 2011 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 6
- Basım Tarihi: 2011
- Doi Numarası: 10.5336/medsci.2009-13956
- Dergi Adı: Turkiye Klinikleri Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1554-1558
- Anahtar Kelimeler: Boutonneuse fever, fever, exanthema, tick-borne diseases
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Mediterranean spotted fever (MSF) is an endemic disease that is caused by R.conorii and spreads with tick bite. Two cases with high fever, headache, muscle pain, extensive macu- lopapular rash involving palms and soles have been followed up in our clinic in July and August 2008. The first case had "tache noire" on his leg. Hepatosplenomegaly was detected in the second case. Leukocyte counts were within normal limits while AST, ALT, LDH and CK levels were increased. BUN and creatinin levels were elevated in the second case. Both cases were considered as MSF based on epidemiological and clinical features and treated with doxycycline. Antibodies against to Rickettsiae were positive with immunoflorescence assay in the sera of both patients. Skin biopsy material was found positive in the first case for R.conorii with polymerase chain reaction method. Both cases were discharged without any complications. © 2010 by Türkiye Klinikleri.