Immunity in allergic diseases
Current Approaches to Allergic Diseases, NOVA Publications , ss.1-11, 2024
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2024
- Yayınevi: NOVA Publications
- Sayfa Sayıları: ss.1-11
- Anahtar Kelimeler: Allergic reactions, Hypersensitivity, Immune system
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The immune system refers to a complicated network that ensures that molecules entering the body are recognized and the required response is provided. Lymphoid organs, cells, humoral factors, and cytokines constitute the main components of this system. The immune system has two main parts: the innate immune system and the acquired immune system. There are many interactions between these two main immune responses. Hypersensitivity, one of the IgE-mediated reactions of mast cells, is among the most powerful reactions of the immune system. Allergens refer to molecules that trigger the occurrence of a hypersensitivity reaction. Allergic inflammation is caused by the mutual interactions of mast cells, lymphocytes, basophils, eosinophils, and neutrophils. The activation of mast cells and the infiltration of eosinophils in the tissue due to IgE are specific to allergic inflammation. The mediators released from mast cells stimulated by IgE lead to the development of a series of pathological responses. Such reactions may emerge as different clinical pictures in individuals. The most common reactions are hay fever, food allergies, asthma, and anaphylaxis.