Recurrent pericarditis as the initial manifestation of Familial Mediterranean fever
Medical Science Monitor, cilt.14, sa.12, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 12
- Basım Tarihi: 2008
- Dergi Adı: Medical Science Monitor
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Familial Mediterranean fever, pericarditis, gene analysis, colchicine
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Familial Mediterranean fever is an autosomal recessive disease largely restricted to certain ethnic groups and presenting with recurrent febrile serositis attacks. Peritonitis, pleuritis, and synovitis are common manifestations; however, the pericardium is rarely affected. Case Report: In this case report, we describe a 25-year-old Turkish woman who presented with recurrent pericarditis of no obvious cause, which eventually responded to colchicine therapy. Using gene mutation analysis to detect the MEFV gene, the patient's condition was finally diagnosed as Familial Mediterranean fever. Conclusions: Familial Mediterranean fever should be considered in patients with idiopathic recurrent pericarditis unresponsive to nonsteroidal anti-inflammatory medications and corticosteroids. Mutation analyses should be done. © Med Sci Monit, 2008.