A case of myositis associated with mixed connective tissue disease mimicking bilateral posterior interosseous nerve palsy Vegyes kötőszöveti betegséghez társuló myositis esete, ami kétoldali posterior interossealis idegbénulást imitál
Ideggyogyaszati Szemle, cilt.78, sa.5-6, ss.211-213, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 78 Sayı: 5-6
- Basım Tarihi: 2025
- Doi Numarası: 10.18071/isz.78.0211
- Dergi Adı: Ideggyogyaszati Szemle
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.211-213
- Anahtar Kelimeler: mixed connective tissue disease, muscle biopsy, overlap myositis, posterior interosseous nerve palsy
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Overlap myositis (OM) is an idiopathic inflammatory myopathy characterized by proximal muscle weakness. However, atypical patterns of muscle involvement may also occur. We present a challenging case of OM mimicking bilateral posterior interosseous nerve (PIN) palsy. The patient presented with a gradual onset of bilateral finger drop over two years. Despite initial clinical suspicion of PIN palsy, electromyography revealed myopathic features. Laboratory assessments showed anti-ribonucleoprotein antibody positivity, with subsequent muscle biopsies supporting OM associated with mixed connective tissue disease. This case highlights the significance of considering atypical presentations of OM. Furthermore, it emphasizes the pivotal role of targeted muscle biopsies when initial biopsy results are inconclusive.