Cardiac cyclic variation of integrated backscatter in hypertension and dialysis patients

AKAR, Harun; Ceyhan, Ceyhun; Yenicerioglu, Yavuz; KEVEN, KENAN; Onbasili, Alper; Tekten, Tarkan

Cardiac cyclic variation of integrated backscatter in hypertension and dialysis patients

AKAR H., Ceyhan C., Yenicerioglu Y., KEVEN K., Onbasili A., Tekten T.

Journal of Nephrology, cilt.17, sa.2, ss.270-274, 2004 (Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 17 Sayı: 2
Basım Tarihi: 2004
Dergi Adı: Journal of Nephrology
Derginin Tarandığı İndeksler: Scopus
Sayfa Sayıları: ss.270-274
Anahtar Kelimeler: end-stage renalfailure, hypertension, cyclic variation of myocardial integrated backscatter
Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Background: Cyclic variation of myocardial-integrated backscatter (CV-IB) offers a non-invasive myocardial contractile performance assessment. There is limited data concerning CV-IB in end-stage renal disease (ESRD) patients. Methods: Forty essential hypertensive (EH) patients (mean age 51 ± 8 yrs) and 24 ESRD patients (mean age 49 ± 14 yrs) were compared to 10 healthy controls (mean age 45 ± 10 yrs). A 2D-Doppler echocardiography with digitized imaging was performed to characterize myocardial ultrasonic tissue by CV-IB between systole and diastole at the interventricular septum (IVS) and left ventricular (LV) posterior wall (PW). Results: There was no significant difference between age and sex among groups. Systolic and diastolic blood pressures (BP) were both higher in EH patients (157/96 mmHg in EH, 129/81 mmHg in ESRD and 115/77 mmHg in controls, p<0.001). Left ventricular mass index (LVMI) was higher in EH and ESRD patients than in controls (respectively, 119 ±37, 130 ± 46, 87 ± 12 g/m2, p<0.05), while there was no significant difference found between EH and ESRD patients. EH patient CV-IB values were significantly lower than in ESRD patients and controls (respectively, 6.9 ± 1.6, 8.6 ± 0.7, 10.6 ± 1.1 dB, p<0.001 for IVS, 7.7 ± 1.3, 8.7 ± 0.8, 10.4 ± 1.1 dB, p<0.001 for PW). CV-IB for PW and IVS were significantly lower in ESRD patients than in controls (p<0.001). Conclusions: CV-IB can offer useful parameters for myocardial structure in EH and ESRD patients. Further studies are needed to clarify CV-IB in ESRD patients.