The Effect of Nasal Staphylococcus Aureus Colonization on Idiopathic Epistaxis Nazal Staphylococcus Aureus Kolonizasyonunun İdiyopatik Epistaksis Üzerine Etkisi


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Savran F., Duymaz Y. K.

Journal of Ear Nose Throat and Head Neck Surgery, cilt.32, sa.4, ss.147-153, 2024 (Scopus, TRDizin)

Özet

Objective: Idiopathic epistaxis is a common condition in children. This study aims to investigate the relation between Staphylococcus aureus and 'idiopathic epistaxis' in paediatric patients with idiopathic epistaxis. Material and Methods: The causes of nosebleeds in patients admitted to the hospital were investigated. After the known causes and the causes revealed by examination were excluded, patients diagnosed with idiopathic epistaxis were included in the study. All blood parameters related to inflammation were evaluated. Nasal swap samples were collected from the nose. Mean platelet volume (MPV), platelet, hemoglobin, hematocrit, lymphocyte, leukocyte, neutrophillymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and systemic immune inflammation index (SII) levels of these patients were compared with age-and sex-matched controls. Results: Eighty six patients were included in the study. Thirty six of 86 patients were female and 50 were male. The mean age was 11.4±5.9 years. The age and gender distribution of the patients did not differ significantly between the groups with and without S. aureus. S. aureus growth was observed in 28 (32.6%) patients. Platelet count, neutrophil count, lymphocyte count, MPV, N/LR, P/LR, and SII values did not differ significantly between groups with and without S. aureus. Conclusion: Our study affirms the colonization of S. aureus in a specific group of idiopathic epistaxis patients. However, no significant differences in systemic inflammatory markers, including NLR, PLR, and SII, were found between patients with and without S. aureus colonization. This indicates that bacterial colonization plays a role in idiopathic epistaxis through local inflammatory effects.