The effects of successful percutaneous mitral balloon valvuloplasty on acute and intermediate term aortic stiffness
Echocardiography, cilt.32, sa.5, ss.813-818, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 5
- Basım Tarihi: 2015
- Doi Numarası: 10.1111/echo.12799
- Dergi Adı: Echocardiography
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.813-818
- Anahtar Kelimeler: mitral stenosis, percutaneous intervention, transthoracic echocardiography
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim The aim of this study was to evaluate the effects of percutaneous mitral balloon valvuloplasty (PMBV) on short- and intermediate-term aortic stiffness in patients with mitral stenosis. Materials and Methods This prospective study included 56 patients with critical mitral stenosis in normal sinus rhythm (68% female; mean age: 42 ± 11 years) and 37 healthy controls. Aortic stiffness was measured using transthoracic echocardiography before PMBV, and 24-48 hours and 1 year post procedure. Results Aortic strain and distensibility were significantly higher in the patients with mitral stenosis, both after PMBV and 1 year post procedure, whereas the aortic stiffness index (ASI) was significantly lower. There was also a significant decrease in mitral mean gradient (MMG) and systolic pulmonary artery pressure (sPAP) after PMBV, based on echocardiography and catheterization. Mitral valve area (MVA) significantly increased after PMBV. There was a significant correlation between change in ΠMVA and ΠMMG and aortic elastic properties. There was a significantly negative correlation between the ΠMVA and ΠΠ aortic stiffness (r = -0.62, P < 0.001), and a significantly positive correlation between ΠMMG and ΠASI (r = 0.60, P < 0.001). Conclusion Mitral valve stenosis was associated with impaired aortic stiffness and following PMBV, aortic stiffness decreased during both the acute period and the intermediate period.