Rare Neoplastic Meningitis in Cerebellar Medulloblastoma Detected by PET/CT
Clinical Nuclear Medicine, cilt.50, sa.6, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 6
- Basım Tarihi: 2025
- Doi Numarası: 10.1097/rlu.0000000000005693
- Dergi Adı: Clinical Nuclear Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Anahtar Kelimeler: F-18-FDG PET/CT, leptomeningeal metastases, cerebellar medulloblastoma
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Neoplastic meningitis, also known as leptomeningeal metastases, is a rare clinical entity seen in less than 1%–2% of primary nervous system tumors. Diagnosis of leptomeningeal metastases is difficult and is achieved by cytologic evidence of malignant cells in cerebrospinal fluid, or demonstration of radiologic abnormality. 18F-FDG PET/CT can detect leptomeningeal metastases before anatomical changes. In this case, a 42-year-old man with cerebellar medulloblastoma underwent surgery and radiotherapy and had FDG uptake in 3 separate locations after 3 months. The findings indicated leptomeningeal metastases, confirmed by MRI. This highlights the role of 18F-FDG PET/CT in detecting leptomeningeal disease postmedulloblastoma treatment.