DOES PREOPERATIVE NEUTROPHIL TO LYMPHOCYTE RATIO AFFECT PREOPERATIVE AND POSTOPERATIVE VAS LEVELS IN PATIENTS UNDERGOING CERVICAL DISC SURGERY?
Journal of Turkish Spinal Surgery, cilt.33, sa.3, ss.91-94, 2022 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 3
- Basım Tarihi: 2022
- Doi Numarası: 10.4274/jtss.galenos.2022.66375
- Dergi Adı: Journal of Turkish Spinal Surgery
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.91-94
- Anahtar Kelimeler: biomarker, cervical disc herniation, Neutrophil to lymphocyte ratio
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Objective: Neutrophil/lymphocyte ratio (NLR) is currently used as a marker for the diagnosis, follow-up and treatment of many diseases. It has been shown immunohistochemically that interleukins and cytokines are released in the disc herniation region. Our aim was to compare visual analog scale (VAS) and NLR values in the patients who have a cervical disc herniation, whom we frequently encounter and operate in neurosurgery practice. Materials and Methods: This study was conducted retrospectively by scanning the files of 24 cervical disc herniation patients that we operated approximately 2018-2020. Magnetic resonance imaging was used for the diagnosis. Patients with a single level cervical disc herniation requiring surgical intervention according to the clinical and radiological findings at the level of C4-5/C5-6/C6-7 were included in the study. Preoperative and postoperative 6th month VAS values were recorded. The neutrophil and lymphocyte ratios were calculated and recorded by taking routine preoperative morning blood samples before surgery. The relationship between VAS and NLR values was examined. Results: Preoperative neutrophil values ranged from 1.77 to 9.35, with a mean of 4.97±1.81. Preoperative lymphocyte values ranged from 1.06 to 4.86, with a mean of 2.54±0.88. NLR values ranged from 0.53 to 4.31, with a mean of 2.12±0.92. A statistically significant decrease in the VAS values was found in the postoperative 6th month compared to the preoperative values (p=0.000; p<0.05). There was a positive (47.7%) and statistically significant correlation between the NLR and preoperative VAS values (p=0.018; p<0.05). Conclusion: The relationship between the NLR and VAS scores in the spinal surgery cases has been evaluated in many series. In our study, we found a positive and significant relationship between the preoperative VAS score and the NLR values, which is consistent with the literature.