Serum Vitamin D Levels and Food Sensitization in Atopic Dermatitis: A Single-center Study Atopik Dermatitli Olgularda Serum D Vitamini Düzeyi ve Besin Duyarlanması: Tek Merkezli Çalışma
Medical Journal of Bakirkoy, cilt.19, sa.4, ss.360-364, 2023 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 19 Sayı: 4
- Basım Tarihi: 2023
- Doi Numarası: 10.4274/bmj.galenos.2023.2022.11-10
- Dergi Adı: Medical Journal of Bakirkoy
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL
- Sayfa Sayıları: ss.360-364
- Anahtar Kelimeler: D vitamine deficiency, food allergy, eczema, atopic dermatitis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Atopic dermatitis (AD) is a chronic, itchy, recurrent, and recurrent inflammatory skin disease that affects 2-20% of the population, especially in childhood. Its pathophysiology is complex and occurs as a result of genetic, immunological, and environmental factors, especially epithelial-barrier dysfunction. We determined the frequency of food sensitization and vitamin D deficiency in patients with AD. Methods: This cross-sectional retrospective study was conducted by examining the files of patients who were admitted to the pediatrics allergy and immunology outpatient clinic with AD. A total of 72 patients with eczema were included in the study. Results: 37.5% (n=27) of the patients were girls. The mean age was 3.8±3.6 years. Food sensitization was proven in 40.2% (n=29) of all cases included in the study. Vitamin D deficiency was found in 30.6% (n=22) of the cases. Serum 25-hydroxyvitamin D3 levels were found to be lower in the patient group than in the control group. The limitation of our study is that it was retrospective and blood tests could not be re-evaluated after treatment in all patients. Conclusion: In patients with AD, serum vitamin D levels were significantly lower. We examined vitamin D deficiency in AD patients who applied to us as a clinical team. According to our study, we can say that both food sensitization and vitamin D deficiency should be investigated in AD patients.