The clinical efficiency of acupuncture in preventing migraine attacks and its effect on serotonin levels Akupunturun migren ataklarının önlenmesinde klinik etkinliği ve serotonin düzeylerine etkisi
Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi, cilt.63, sa.1, ss.59-65, 2017 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 63 Sayı: 1
- Basım Tarihi: 2017
- Doi Numarası: 10.5606/tftrd.2017.45578
- Dergi Adı: Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.59-65
- Anahtar Kelimeler: Acupuncture, migraine, serotonin
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objectives: This study aims to investigate the efficacy of acupuncture in preventing migraine attacks. Patients and methods: Between December 2013 and June 2014, a total of 54 patients with a diagnosis of migraine in our neurology clinic were randomized into two groups. Venlafaxine was administered for three months to one group (drug therapy group: 4 males, 21 females; mean age 32.0±9.1 years; range, 18 to 65 years), while the other group was treated with acupuncture (acupuncture group: 5 males, 24 females; mean age 30.3±7.4 years; range, 18 to 65 years). The control group consisted of a total of 29 healthy individuals (7 males, 22 females; mean age 30.3±7.4 years; range 18 to 65 years). Blood serotonin levels were assessed before and after treatment along with visual analog scale (VAS) and Migraine Disability Assessment (MIDAS) in both groups. Results: There was no statistically significant difference in the mean analgesic use before and after the treatment and VAS and MIDAS scores between the acupuncture and drug therapy groups (p>0.05). The number and duration of attacks was found to be significantly lower in both groups, compared to the pre-treatment values (p<0.0001). The serotonin levels in the acupuncture and drug therapy groups were significantly higher compared to the pre-treatment values (p<0.001). Serotonin levels were found to be significantly lower in healthy individuals compared to the study groups (p<0.0001). Conclusion: Based on our study findings, acupuncture may be an effective option in the migraine prophylaxis.