SEPSIS DUE TO LISTERIA MONOCYTOGENES IN AN IMMUNOCOMPROMISED PATIENT WITH PERITONEAL CARCINOMATOSIS: A CASE REPORT BAĞIŞIKLIĞI BASKILANMIŞ, PERİTONEAL KARSİNOMATOZİSLİ BİR HASTADA LISTERIA MONOCYTOGENES’E BAĞLI SEPSİS: OLGU SUNUMU

Unat İ., TEKİN K., DURMAZ M. O., AYKAN M. B., HOŞBUL T.

Istanbul Tip Fakultesi Dergisi, cilt.86, sa.2, ss.176-179, 2023 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 86 Sayı: 2
  • Basım Tarihi: 2023
  • Doi Numarası: 10.26650/iuitfd.1208626
  • Dergi Adı: Istanbul Tip Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.176-179
  • Anahtar Kelimeler: Hyperthermic intraperitoneal chemotherapy, Listeria monocytogenes, peritoneal carcinomatosis, systemic chemotherapy, sepsis
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Listeria monocytogenes is an opportunistic infectious agent that can cause self-limiting gastroenteritis in immunocompetent individuals, usually with the consumption of contaminated foods, and fatal infections in immunocompromised individuals and newborns. Local effects of intra-abdominal tumors, immune response suppression, and operations that disrupt the integrity of the peritoneal membrane and gastrointestinal tract may increase the risk of pathogen-induced invasive infection. Although cytoreductive surgical interventions, systemic and/or hyperthermic intraperitoneal chemotherapy (HIPEC) applied in the treatment of patients with abdominal and pelvic malignancies increase disease-free survival, they may predispose to infections caused by L. monocytogenes through gastrointestinal and systemic complications. In this case report, a 71-year-old male patient diagnosed with sepsis due to L. monocytogenes after treatments with systemic chemotherapy and cytoreductive surgery combined with HIPEC is discussed. It is aimed to raise clinical and laboratory awareness that L. monocytogenes may cause systemic and life-threatening infections in individuals whose immune system is suppressed due to cancer, surgical procedures, and the use of chemotherapeutic agents.