Role of the vitreous in age-related macular degeneration
Japanese Journal of Ophthalmology, cilt.44, sa.1, ss.91-93, 2000 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 44 Sayı: 1
- Basım Tarihi: 2000
- Doi Numarası: 10.1016/s0021-5155(99)00174-4
- Dergi Adı: Japanese Journal of Ophthalmology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.91-93
- Anahtar Kelimeler: age-related macular degeneration, posterior vitreous detachment, retina, vitreous
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: To investigate the relationship between posterior vitreous detachment (PVD) and age-related macular degeneration (AMD). Methods: The condition of the vitreous was examined by slit-lamp funduscopy and ultrasonography in 93 eyes of 50 patients with AMD (exudative or dry) and 100 eyes of 50 controls. Results: There was complete PVD in 31 of the 93 eyes (33.3%) of 50 patients with AMD and the posterior vitreous was attached in 62 of these eyes (66.6%). In the control group, in 50 eyes (50%) of 50 subjects there was posterior vitreous detachment. The prevalence of PVD in eyes with macular degeneration was significantly lower (P < .05). There was no statistically significant difference between the exudative and the nonexudative groups in respect to PVD. Conclusions: PVD may have a protective role against the development of AMD. Chronic vitreomacular traction and/or continuous exposure to free radicals and cytokines may possibly be one of the causes of AMD in eyes with attached vitreous. Copyright (C) 2000 Japanese Ophthalmological Society.