Acute hemolysis in association with hepatitis B infection in a child with beta-thalassemia trait.


Gürgey A., Yüce A., ÖZBEK N. Y., KOÇAK N. C.

The Turkish journal of pediatrics, cilt.36, sa.3, ss.259-262, 1994 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 3
  • Basım Tarihi: 1994
  • Dergi Adı: The Turkish journal of pediatrics
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.259-262
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Autoimmune hemolytic anemia may occur in the course of some viral diseases such as Coxsackie virus, cytomegalovirus, Epstein Barr virus, Influenza A, herpes simplex virus, and rarely hepatitis B virus infection. The role of being heterozygous for beta-thalassemia in hemolysis during acute viral hepatitis is not known. In this report, we present an eight-year-old boy with jaundice and anemia. The diagnosis of hepatitis B virus infection and hemolytic anemia were made on the basis of physical and laboratory findings. A hemoglobin electrophoresis revealed that the child was heterozygous for beta-thalassemia. No specific etiology could be found for hemolytic anemia. It remained unclear whether hemolytic anemia in this patient was merely a coincidental finding or whether hepatitis B virus infection and beta-thalassemia trait had played a role in causing hemolysis.