Poor Tc-99m dimercaptosuccinic acid uptake, re-evaluation with Tc-99m MAG3 scintigraphy in Lowe syndrome
Indian Journal of Nuclear Medicine, cilt.26, sa.4, ss.185-187, 2011 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 26 Sayı: 4
- Basım Tarihi: 2011
- Doi Numarası: 10.4103/0972-3919.106701
- Dergi Adı: Indian Journal of Nuclear Medicine
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.185-187
- Anahtar Kelimeler: Lowe syndrome, Tc-99m dimercaptosuccinic acid, Tc-99m MAG3
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Tc-99m dimercaptosuccinic acid (DMSA) is filtered through the glomeruli and reabsorbed by the proximal tubules as low molecular weight proteins. In Lowe syndrome this mechanism is impaired and so poor DMSA uptake is seen. Poor DMSA uptake was shown in very few studies, but none mentioned normal Tc-99m MAG3 uptake. In this case, the patient had poor DMSA uptake, normal MAG3 uptake and a neurogenic bladder in anterior to the left kidney that attenuates left kidney.