Meniere's disease during pregnancy and the postpartum period
ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation, Springer International Publishing Ag, ss.483-493, 2022
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2022
- Doi Numarası: 10.1007/978-3-031-05303-0_35
- Yayınevi: Springer International Publishing Ag
- Sayfa Sayıları: ss.483-493
- Anahtar Kelimeler: Inner ear, Meniere's disease, Otolaryngology, Postpartum period, Pregnancy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Meniere's disease (MD) is a syndrome characterized by attacks of recurrent spontaneous vertigo, sensorineural hearing loss, tinnitus, and aural fullness. Clinically, we can divide the course of the disease into three periods: initial, active, and final. However, pregnancy is of particular importance in female patients in terms of the course of the disease. Hormones such as human chorionic gonadotropin (HCG) secreted during pregnancy and increased estrogen and progesterone levels can increase vertigo attacks in Meniere's disease by various mechanisms. In particular, it has been shown that estrogen increases endolymphatic hydrops (EH) by affecting the aquaporin receptors in the inner ear through the arginine vasopressin (AVP) system. In addition, it is thought that decreased body osmolality during pregnancy due to the effect of these hormonal changes also triggers vertigo. In the postpartum period, it is said that prolactin can worsen Meniere's symptoms by increasing anxiety and depression.