Comparison of the Efficacy of 2 Different Botulinum Toxin Injection Techniques in Gastrocnemius Muscle Spasticity in Hemiplegic Patients: A Randomized Double-Blind Controlled Study
Archives of Physical Medicine and Rehabilitation, cilt.106, sa.3, ss.327-332, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 106 Sayı: 3
- Basım Tarihi: 2025
- Doi Numarası: 10.1016/j.apmr.2024.09.011
- Dergi Adı: Archives of Physical Medicine and Rehabilitation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MLA - Modern Language Association Database, Nature Index
- Sayfa Sayıları: ss.327-332
- Anahtar Kelimeler: Botulinum toxin, Hemiplegia, Injection technique, Rehabilitation, Spasticity
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: To compare the efficacy of the innervation zone–targeted injection technique (EUROMUSCULUS/USPRM (Ultrasound Study Group of the International Society of Physical and Rehabilitation Medicine) spasticity approach) and the injection technique along the muscle length. Design: A double-blind randomized controlled trial. Setting: Department of rehabilitation medicine of a medical center. Participants: One hundred patients with stroke experiencing ankle plantar flexor spasticity. Interventions: In addition to conventional rehabilitation, eligible patients were randomly assigned to 2 groups. The experimental group was injected with botulinum toxin along the length of the muscle, whereas the control group was injected with the same dose and volume of botulinum toxin 25%-35% proximal to the medial head and 20%-30% proximal to the lateral aspect of the head of the gastrocnemius muscle. Main Outcome Measures: Modified Ashworth scale, modified Tardieu scale, ankle range of motion measurement, and 10-meter walk test were used before and 1 month after injection. Results: The study was completed by 60 participants with a mean age of 59.96±12.15 years. Both injection methods were found to be effective on range of motion, spasticity level, ambulation, and walking speed. There was no statistically significant difference between injection methods. Conclusions: Both injection methods of botulinum toxin A produce similar clinical effects.