Evaluation of Concordance Between Intraoperative Frozen Section and Final Histopathology in Adnexal Masses
Eastern Journal of Medicine, cilt.31, sa.1, ss.35-40, 2026 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 1
- Basım Tarihi: 2026
- Doi Numarası: 10.5505/ejm.2026.84809
- Dergi Adı: Eastern Journal of Medicine
- Derginin Tarandığı İndeksler: Scopus, EMBASE, TR DİZİN (ULAKBİM), Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest), Pharma Collection (ProQuest)
- Sayfa Sayıları: ss.35-40
- Anahtar Kelimeler: Adnexal Mass, Frozen Section, Gynecological Oncology, Histopathology, Ovarian Neoplasms
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The aim of this study was to evaluate the concordance between intraoperative frozen-section diagnosis and final paraffin-embedded histopathological examination in patients operated for adnexal masses, in order to assess the reliability of frozen-section analysis for intraoperative decision-making. Data from 50 patients who underwent surgery between September 2024-November 2025, for adnexal masses at the Gynecology Department of Gaziantep City Hospital and had intraoperative frozen-section evaluation followed by final pathology were retrospectively analyzed. Demographic, clinical, radiological, laboratory (tumor markers), surgical (laparoscopy vs. laparotomy), and pathological data (frozen and final diagnoses) were collected. The median age of patients was 47.8 years (range 34–74), and the median BMI was 32.4 kg/m² (range 24–42). The median preoperative blood CA-125 level was 86 U/mL (range 8–760), with 60% of patients exceeding 35 U/mL. Median tumor size was 13.7 cm (range 6–32), and 80% of masses were unilateral. Intraoperative frozen-section diagnosed 52% as benign, 20% as borderline (“most likely,” borderline or “at least borderline”), and 16% as malignant. Final histopathology revealed 60% benign, 16% borderline, and 24% malignant tumors. The majority of surgeries were performed via laparotomy (72%). In this cohort, frozen-section diagnosis demonstrated a high rate of agreement with final pathology for benign and malignant adnexal masses supporting its role as a valuable intraoperative tool for guiding surgical management.