Metastatic squamous cell cancer with unknown primary origin in the mediastinal lymph node


AĞCA M., Kosif A.

Nigerian Journal of Clinical Practice, cilt.21, sa.10, ss.1384-1386, 2018 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 10
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4103/njcp.njcp_149_18
  • Dergi Adı: Nigerian Journal of Clinical Practice
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1384-1386
  • Anahtar Kelimeler: Mediastinal lymph node, neoplasm, unknown primary tumor
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Metastatic tumors with unknown primary origin are a group of heterogeneous tumors with undetectable primary tumor site on admission. They have the common properties of rapid and aggressive progression and unpredictable metastases. They form 3%-5% of all cases with cancer and the fourth-most common cause of cancer-related deaths. The histological type of these tumors is commonly (90%) adenocarcinoma, whereas 5% are squamous cell carcinomas. Metastasis is observed in the liver, lungs, and bones. Mediastinal lymph node metastasis is extremely rare. They have a poor prognosis and the mean survival is shorter than a year. The case we have presented is a rare case due to its mediastinal lymph node involvement among tumors with unknown origin and squamous cell histological subtype.