Heparin-induced thrombocytopenia association with impaired liver function tests Bozulmuş Karaciğer Fonksiyon Testleri ile Heparine Bağlı Trombositopeni Birlikteliği
Journal of Clinical and Analytical Medicine, cilt.7, ss.107-109, 2016 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 7
- Basım Tarihi: 2016
- Doi Numarası: 10.4328/jcam.1745
- Dergi Adı: Journal of Clinical and Analytical Medicine
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.107-109
- Anahtar Kelimeler: Heparin-induced Thrombocytopenia, Liver Damage, Arterial Thrombosis, Children
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Heparin-induced thrombocytopenia is an intensely procoagulant disorder and car-ries significant morbidity and mortality. However, the elevations in serum amino-transferases are characteristically asymptomatic and reversible with treatment termination. The serious liver injury due to heparins has not been reported but liver function should be monitored closely since potential severe liver damage with hepatocyte necrosis can occur. In this case report, we present a one-year-old male patient who developed a left lower extremity arterial thrombosis follow-ing an pulmonary artery banding procedure. Our case was taking unfractionated heparin for anticoagulation. On the third day of heparin therapy, routine blood analysis revealed deranged hepatic function tests and thrombocytopenia. Unfrac-tionated heparin treatment was discontinued and he was treated with therapeutic doses of low-molecular-weight heparin for arterial thrombosis. His platelet count and liver function tests had normalised 2 weeks later.