Awareness of glucose-6 phosphate-dehydrogenase deficiency in celiac disease
Acta Paediatrica, International Journal of Paediatrics, cilt.99, sa.5, ss.786-788, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 99 Sayı: 5
- Basım Tarihi: 2010
- Doi Numarası: 10.1111/j.1651-2227.2009.01669.x
- Dergi Adı: Acta Paediatrica, International Journal of Paediatrics
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.786-788
- Anahtar Kelimeler: Anaemia, Celiac disease, Coagulopathy, Glucose-6 phosphate-dehydrogenase deficiency
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Individuals with celiac disease (CD) are predisposed to a number of haematological abnormalities including anaemia secondary to malabsorption of iron, vitamin B12 or folate; anaemia of chronic disease and coagulopathy secondary to vitamin K deficiency. Correction of coagulopathy with vitamin K is necessary before endoscopic biopsy in patients with suspected CD. However, vitamin K causes haemolysis in glucose-6 phosphate-dehydrogenase deficiency. Conclusion: When vitamin K administration becomes necessary for correction of coagulopathy in patients with CD; glucose-6 phosphate-dehydrogenase deficiency should be considered. © 2010 Foundation Acta Pædiatrica.