Clinical outcomes of double kissing crush or double kissing culotte technique in left main bifurcation lesions: the MAIN-ROUTE registry

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ERTÜRK M., KAHRAMAN S., Karabay C. Y., ERDÖL M. A., ARI H., DURMAZ E., ...Daha Fazla

Postepy w Kardiologii Interwencyjnej, cilt.21, sa.3, ss.305-313, 2025 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 3
  • Basım Tarihi: 2025
  • Doi Numarası: 10.5114/aic.2025.154307
  • Dergi Adı: Postepy w Kardiologii Interwencyjnej
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.305-313
  • Anahtar Kelimeler: left main coronary artery, bifurcation lesion, double kissing culotte, double kissing crush
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Introduction: Percutaneous coronary intervention (PCI) of a left main coronary artery (LMCA) bifurcation lesion is a challenging topic among interventional cardiologists. The optimal stenting modality for patients requiring a 2-stent strategy is still debated. Aim: To compare the clinical outcomes of double kissing (DK) crush and DK culotte techniques in distal LMCA bifurcation lesions. Material and methods: Patients with unprotected distal LMCA bifurcation lesions undergoing PCI with DK crush or DK culotte technique were enrolled in 9 heart centers. The primary endpoint of the study was target lesion failure (TLF) as a composite endpoint of target lesion revascularization (TLR), target vessel myocardial infarction (TVMI), and cardiac death. Results: A total of 245 patients with unprotected distal LMCA bifurcation lesions treated with DK culotte (121 patients) or DK crush (124 patients) technique were followed up for 3 years. The incidence of 3-year TLF was lower in the DK culotte group than the DK crush group (5.0% vs. 11.3%, HR = 0.557, 95% CI: 0.211–1.471; p = 0.06). There was also no difference in 3-year TLR (5.0% vs. 7.3%, HR = 0.907, 95% CI: 0.310–2.651; p = 0.42), TVMI (2.5% vs. 3.2%, HR = 0.762, 95% CI: 0.160–3.627; p = 0.71), or cardiac death (0.8% vs. 2.4%, HR = 0.733, 95% CI: 0.063–8.550; p = 0.32) between groups. Conclusions: In the present multicenter study, the DK culotte group had a lower TLF ratio than the DK crush group, without a statistically significant difference in distal true left main bifurcation lesions.