Antibacterial effects of nanoparticles, composite quantum dots and silk proteins attached to dental titanium alloy
American Journal of Dentistry, cilt.36, sa.4, ss.163-171, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 4
- Basım Tarihi: 2023
- Dergi Adı: American Journal of Dentistry
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE
- Sayfa Sayıları: ss.163-171
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: To present the antibacterial effect of new generation boron-doped carbon quantum dots (B-CQD) and compare the antibacterial effect of silk sericin (SS), hydrolyzed silk peptide (HSP) and SSIHSP coated silver nanoparticle (AgNP) and B-CQDs on titanium alloy (Ti) surfaces. Methods: SS and HSP were formed on the surface of the Ti alloy (Ti-SSIHSP). Different concentrations of citric acid and boric acid, B-CQDs and AgNP were attached to Ti-SSIHSP surfaces. To characterize all samples, Fourier Transform Infrared (FTIR), scanning electron microscopy (SEM) and energy dispersive X-ray (EDS) analyses were performed. Their antibacterial potential was analyzed against gram-positive Staphylococcus aureus (S. aureus) and gram-negative Pseudomonas aeruginosa (P. aeruginosa) with Mueller-Hinton Test. One-way ANOVA was used to assess any difference between groups. P< 0.05 was considered statistically significant. Results: No antibacterial activity was detected for Ti and SSIHSP. Inhibition holes ranged from 11 mm to 25.7 ± 3.2 mm and 11 mm to 26.3± 0.6 mm in the S. aureus and P. aeruginosa cultures respectively, showing that AgNP was the molecule which had the least antibacterial effect regardless of type of bound silk protein on both bacteria, and B-CQD had antibacterial superiority against S. aureus and P. aeruginosa on Ti-SS surfaces.