The use of alpha blockers in the treatment of benign prostatic hyperplasia Benİgn Prostat Hİperplazİsİ Tedavİsİnde Alfa Bloker Kullanimi
Turk Geriatri Dergisi, cilt.15, sa.2, ss.237-240, 2012 (SCI-Expanded, SSCI, Scopus, TRDizin)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 15 Sayı: 2
- Basım Tarihi: 2012
- Dergi Adı: Turk Geriatri Dergisi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.237-240
- Anahtar Kelimeler: Adrenergic alpha-antagonist, Prostate, Prostatic hyperplasia
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Lower urinary tract symptoms due to benign prostate hyperplasia is a most common urological problem affecting older men. The dynamic and static components in benign prostatic hyperplasia cause the infravesical obstruction and related lower urinary tract symptoms. Nowadays, there are two main treatment modalities as medical and surgical for benign prostate hyperplasia. Alpha blockers and 5-· reductase inhibitor drugs have been the most favorite agents in the medical treatment of benign prostate hyperplasia. Alpha 1 adrenoceptor antagonists are an important medical option in the management of lower urinary tract symptoms. These agents reduce smooth muscle tone in the prostate and lower urinary tract by inhibiting sympathetic alpha 1 adrenoceptor stimulation, thereby relaxing the bladder outlet and improving urinary flow. In this article the use of alpha-receptor blocker drugs have been summarized.