TIVA and intragastric pH during open heart surgery KARDIYOPULMONER BYPASS'DA TOTAL INTRAVENOZ ANESTEZI VE INTRAGASTRIK PH
Turk Anesteziyoloji ve Reanimasyon, cilt.23, sa.2, ss.70-73, 1995 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 23 Sayı: 2
- Basım Tarihi: 1995
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.70-73
- Anahtar Kelimeler: Cardiopulmonary bypass, Intragastric pH, TIVA
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
It is planned to study the intragastric pH during premedication, induction, perfusion, hypothermia and postoperative period. Total intravenous anaesthesia was used in these 20 patients who had been scheduled for coronary artery bypass surgery. Patients were premedicated with 10 mg diazepam PO the night before. In the morning after being hungry for 8 hours, before surgery morphine 10 mg IM and diazepam 10 mg PO was administered Fentanyl 30 μg/kg, diazepam 0.5 mg/kg and 0.1 mg/kg pancuronium were administered as induction agents. Maintenance of anaesthesia has been achieved with fentanyl and pancuronium. After the induction a digital pH meter nasogastric catheter was inserted, pH values were recorded after induction, during cross clamp, bypass, after by-pass and post op 4th hour. A mean control value was obtained by catheter introduced to awake non-cardiac patients. Although the mean pH value in control group was 2.4; the intragastric pH of the operation group after induction was 4.69, during hypothermia pH value was 4.90, and at 35°C during rewarming period the warmest pH value was 4.86. Mean pH value after bypass was 4.90 and at the post op 4th hour mean pH value was 4.79 (p<0.05). Although the intragastric pH didn't change the CO, PVR and SVR values were statistically different after induction and after by-pass (p<0.05), (p<0.05). There was no correlation between hemodynamic parameters and pH values. The results suggested that premedication and induction with diazepam ended with alkaly intragastric pH and this alkaly pH remained as alkaly both during perfusion hypothermia and rewarming periods and post op 4th hour. The usage of other agents with diazepam is very important with regard to their effects on intragastric pH.