The association between cognitive function and physical performance in established users of a lower limb prosthesis
Irish Journal of Medical Science, cilt.194, sa.5, ss.1915-1921, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 194 Sayı: 5
- Basım Tarihi: 2025
- Doi Numarası: 10.1007/s11845-025-04049-5
- Dergi Adı: Irish Journal of Medical Science
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.1915-1921
- Anahtar Kelimeler: Amputation, Cognition, Physical functional performance
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Cognitive abilities are important for mobility functions in individuals with amputation. Aims: To investigate the association between cognitive function and physical performance in established users of a lower limb prosthesis. Methods: This prospective cross-sectional study was included established users of a lower limb prosthesis (N = 62; mean age ± SD, 41.33 ± 14.76 years). The Montreal Cognitive Assessment was used to evaluate cognitive function. The Timed Up and Go Test under single-task and dual-task conditions, the Four Square Step Test, and the 3-m Backward Walk Test were used for physical performance assessment. Results: An independent association was found of the Montreal Cognitive Assessment to the dual task Timed Up and Go Test (AdjR2 = 0.168, p = 0.003), the Four Square Step Test (AdjR2 = 0.25, p = 0.003) and the 3-m Backward Walk Test (AdjR2 = 0.159, p = 0.032). An increase of 1 point in the Montreal Cognitive Assessment was associated with a reduction of 0.681 s (95% CI, 1.116–0.246) in the the dual task Timed Up and Go Test, 0.378 s (95% CI, 0.617–0.138) in the Four Square Step Test, and 0.255 s (95% CI, 0.487–0.022) in the 3-m Backward Walk Test. Conclusions: The results of this study revealed an independent association between global cognitive function and functional mobility under dual-task conditions, dynamic balance, and backward walking performance in established users of a lower limb prosthesis. These results emphasize that cognitive functions should be taken into account in interventions aimed at improving challenging physical performance in established users of a lower limb prosthesis.