The Role of Shock Indices in Determining Transfusion in Patients with Sepsis Sepsisli Hastalarda Transfüzyonu Belirlemede Şok İndekslerinin Rolü
Genel Tip Dergisi, cilt.31, sa.2, ss.125-129, 2021 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.15321/geneltipder.2021.298
- Dergi Adı: Genel Tip Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.125-129
- Anahtar Kelimeler: Age Shock Index, Erythrocyte Transfusion, Intensive Care Unit, Modified Shock Index, Sepsis, Shock Index
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Shock indices are especially used in hemorragic shocks in order to predict if transfusion is needed or not. But there is not sufficient data for the usage of shock indices in order to predict transfusion needs for septic patients. In this study, we aimed to determine the availibility of shock index (SI), modified shock index (MSI) and age shock index (ASI) for the predicition of transfusion needs in septic and septic shock pateints. Material and Methods: We retrospectively evaluated the results of patients who were hospitalized in ICU, between November 1, 2017 and December 31, 2018. We recorded age, gender, co-morbidities, acute physiology and chronic health evaluation II (APACHE II) scores, length of mechanical ventilation, length of hospital stay, hemoglobin levels, SI, MSI and ASI, erythrocyte transfusion requirement. Results: We evaluated 225 patients. SI, MSI and ASI levels were significantly higher in patients requiring erythrocyte transfusion compared with patients not receiving transfusion (p < 0.05). For SI, the area under the receiver operating characteristic (ROC) curve was 0.691 (95% confidence interval (CI): 0.626–0.751, p = 0.0002) and cutoff value for transfusion was 0.98 (sensitivity: 86.8%, 95% CI: 71.9-95.5; specificity: 46.52%, 95% CI: 39..2-53.9). For MSI, the area under the ROC curve was 0.666 (95% CI: 0.601–0.728, p = 0.0012) and cutoff value for transfusion was 1.67 (sensitivity: 57.9%, 95% CI: 40.8-73.7; specificity: 72.7%, 95% CI: 65.7-79). For ASI, the area under the ROC curve was 0.639 (95% CI: 0.572–0.702, p = 0.0076) and cutoff value for transfusion was 102.85 (sensitivity: 39.5%, 95% CI: 21.4–56.6; specificity: 89.8%, 95% CI: 84.6–93.8). Discussion: Shock indices can be used in septic pateints in order to predict their erytocyte transfusion needs. Additional parameters are needed to be used toget-her with septic indices.