Relationship of Renal Sinus Fat and Circadian Blood Pressure in Patients with Hepatosteatosis: A New Perspective from a Retrospective Study
Medicina (Lithuania), cilt.62, sa.7, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 62 Sayı: 7
- Basım Tarihi: 2026
- Doi Numarası: 10.3390/medicina62071406
- Dergi Adı: Medicina (Lithuania)
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals, Health Research Premium Collection (ProQuest)
- Anahtar Kelimeler: renal sinus fat, hepatosteatosis, circadian blood pressure, dipper, hypertension, non-dipper
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background and Objectives: Renal sinus fat accumulation affects many diabetic processes, including blood pressure. The aim of this study was to find out if there is a link between the amount of fat in the renal sinus and the blood pressure that changes throughout the day in adults with non-alcoholic fatty liver disease (NAFLD). Materials and Methods: This retrospective analysis involved 55 adult patients diagnosed with non-alcoholic fatty liver disease (NAFLD) based on abdominal computed tomography (CT) and who had undergone 24 h ambulatory blood pressure monitoring (ABPM). According to standard ABPM criteria, individuals whose night-time systolic blood pressure decreased by ≥10% compared to daytime values were classified as “dippers,” whereas those with a reduction of <10% were classified as “non-dippers”. Results: The non-dipper group had a significantly higher leukocyte count (p = 0.012). Renal sinus fat volume (RSFV) was significantly larger in the non-dipper group (6.41 ± 3 mL) than the dipper group (4.12 ± 2.26 mL; p = 0.005). In the ROC curve analysis showing the role of RSFV in predicting the non-dipper blood pressure pattern, the threshold value for RSFV in our cohort was determined as ≥3.7 mL with a positive predictive value of 72.2%. Conclusions: Our findings indicated that RSFV plays a significant role in predicting the non-dipper blood pressure profile among individuals diagnosed with NAFLD. Participants with an RSFV of 3.7 mL or more in our cohort were more likely to exhibit a non-dipping blood pressure pattern. Future studies are needed to validate these findings in larger cohorts.