Investigating the role of dietary glycemic factors and antioxidant capacity, metabolic status, and oxidative stress in seborrheic dermatitis: A case-control study
Journal of the American Academy of Dermatology, cilt.92, sa.3, ss.503-510, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 92 Sayı: 3
- Basım Tarihi: 2025
- Doi Numarası: 10.1016/j.jaad.2024.10.078
- Dergi Adı: Journal of the American Academy of Dermatology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, Nature Index
- Sayfa Sayıları: ss.503-510
- Anahtar Kelimeler: diet, glycemic load, metabolic syndrome, seborrheic dermatitis, total antioxidant capacity
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: The etiopathogenesis of seborrheic dermatitis (SD) remains unexplained, although several factors have been considered in this regard. Objective: The aim of this study is to investigate diet, metabolic status, and oxidative stress in SD patients. Methods: This prospective, single-center, case-control study included 49 SD patients and 40 gender- and age-matched healthy controls. Results: Dietary total antioxidant capacity values were significantly lower in SD patients than among the controls (7.16 ± 2.66 vs 12.85 ± 4.26; P < .001). Glycemic load (GL) values were significantly higher in SD patients (187.2 ± 57.2 vs 110.6 ± 46.5; P < .001). The glycemic index and GL values of patients with severe SD were significantly higher than those with mild SD (P = .014, P = .017; respectively). Limitations: The cross-sectional design, small sample size, and the relatively short duration of questioning dietary habits are the limitations of the study. Conclusion: A diet rich in antioxidants and with low glycemic index/GL content may be beneficial in the treatment of SD.