Childhood Vaccinations in Children With Food or Vaccination-Related Allergic Reactions: A Single-Center Experience
Clinical Pediatrics, cilt.65, sa.2, ss.169-176, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 65 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.1177/00099228251354850
- Dergi Adı: Clinical Pediatrics
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EBSCO Education Source, EMBASE, MEDLINE, Public Affairs Index, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Education Source Ultimate (EBSCO), Health Research Premium Collection (ProQuest), Sociology Source Ultimate (EBSCO)
- Sayfa Sayıları: ss.169-176
- Anahtar Kelimeler: childhood vaccination programs, children, food allergy, vaccination-related allergic reactions, vaccine, MMR vaccine, alpha-lactalbumin, immunization, vaccine anaphylaxis, measles vaccine
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Children with allergic reactions are mostly referred to tertiary centers for vaccination, but confirmed vaccination-triggered allergic reactions are uncommon. In this study, childhood vaccination-triggered allergic reactions in children with food and vaccination-related allergies are evaluated. Methodology: Retrospective analysis of 923 doses of vaccine administered in our clinic due to food or vaccine-triggered allergic reactions were conducted. Results: 868 vaccines were measles-mumps-rubella (MMR) vaccine, 20 were measles vaccine containing alpha-lactalbumin and 35 were other childhood vaccines. A total of 576 of MMR vaccines contained alpha-lactalbumin and 292 did not. Vaccinations were administered without any reactions in 98.9% of patients with previous food allergies. One of the reactions was anaphylaxis. About 55 patients were referred because of previous vaccination-related allergic reactions, and 94.5% of them were vaccinated without any reactions. Mild reactions were encountered in 3 (5.5%) patients. No anaphylaxis was observed. Conclusion: Patients with a history of food or vaccination allergies have a low rate of allergic reactions in childhood vaccinations.