Association between mean platelet volume and treatment duration in children with nephrotic syndrome Nefrotik sendromlu çocuklarda ortalama trombosit hacminin tedavi süresine etkisi
Haseki Tip Bulteni, cilt.50, sa.1, ss.6-9, 2012 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 1
- Basım Tarihi: 2012
- Dergi Adı: Haseki Tip Bulteni
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.6-9
- Anahtar Kelimeler: Child, Mean platelet volume, Nephrotic syndrome, The response time to therapy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: The aim of our study was to determine the relationship between mean platelet volume (MPV) and duration of response to treatment in children with steroid-sensitive nephrotic syndrome (SSNS). Patients and Methods: This is a retrospective study which included 32 children with SSNS. The control group consisted of 32 age- and gender-matched healthy children. Results: The mean age of the children with SDNS (21 males) was 6.45±3.71 years and that of controls (20 males) 6.81±1.97 years. The duration of response to steroid therapy of the patients was 14.7±6.8 days. While there were no relationship between duration of treatment and the MPV, duration of treatment was inversely correlated with red blood cell count (r=-0.484, p=0.005). Conclusion: There was not an association between the MPV and the duration of response to treatment. However, the response time to treatment was increased with a decrease in number of erythrocytes. We may interpret this situation as follows: a decrease in red blood cell count may result in reduced delivery of oxygen to tissues.