Carbon Dioxide Elimination With Flow-Controlled Ventilation in Lung Transplantation: A Case Report
Transplantation Proceedings, cilt.58, sa.2, ss.374-377, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 58 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.1016/j.transproceed.2026.01.005
- Dergi Adı: Transplantation Proceedings
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE, Academic Search Ultimate (EBSCO)
- Sayfa Sayıları: ss.374-377
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Lung transplantation represents the most definitive treatment option for patients with advanced-stage lung diseases. In recent years, improvements in anesthetic techniques, medical technologies, and coordinated perioperative care have contributed to better survival outcomes. Case Presentation: A 37-year-old male patient with a height of 168 centimeters and a weight of 70 kilograms, diagnosed with cystic fibrosis, was scheduled for bilateral lung transplantation. Shortly after transitioning to single-lung ventilation, a rapid and severe increase in carbon dioxide levels was observed, reaching 136 mm Hg, accompanied by a decrease in blood pH to 7.0, indicating pronounced respiratory acidosis. In response, flow-controlled ventilation was applied for 6 hours during the eleven-hour surgical procedure. Conclusions: Although the patient's respiratory profile initially suggested the need for extracorporeal membrane oxygenation, the application of flow-controlled ventilation appeared to improve carbon dioxide elimination and may have reduced the risk of complications related to extracorporeal support. This case indicates that flow-controlled ventilation could be considered a supportive ventilation strategy to avoid extracorporeal membrane oxygenation in selected patients undergoing lung transplantation who develop isolated intraoperative respiratory insufficiency.