Effective treatment of undiferentiated pleomorphic sarcoma using gemcitabine: A case report
Turk Onkoloji Dergisi, cilt.33, sa.4, ss.162-165, 2018 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 4
- Basım Tarihi: 2018
- Doi Numarası: 10.5505/tjo.2018.1771
- Dergi Adı: Turk Onkoloji Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.162-165
- Anahtar Kelimeler: Cardiac failure, complete remission, gemcitabine, undifferentiated pleomorphic sarcoma
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Undifferentiated pleomorphic sarcoma (UPS) is most frequently observed in the extremities but rarely in the retroperitoneum. The present treatment for patients with metastatic or unresectable UPS in the first-line setting includes doxorubicin administration with or without ifosfamide. We present a case of a 68-year-old woman who presented with a retroperitoneal giant mass. The patient underwent surgery, the mass was removed, and the final diagnosis was UPS. The postoperative stage included soft tissue metastases. After three cycles of gemcitabine chemotherapy, computed tomography findings revealed the absence of soft tissue metastases. The patient has remained on regular follow-up over the past two years since chemotherapy with no symptoms of disease recurrence. The findings of this case demonstrate that patients with retroperitoneal UPS may benefit from single-agent gemcitabine chemotherapy.