Comparison of a TrachoSpray Device and Manual Lidocaine Spray on Hemodynamic Stability and Postoperative Sore Throat in Patients Undergoing Double-Lumen Tube Intubation: A Randomized Controlled Trial
Journal of Investigative Surgery, cilt.39, sa.1, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 39 Sayı: 1
- Basım Tarihi: 2026
- Doi Numarası: 10.1080/08941939.2025.2586017
- Dergi Adı: Journal of Investigative Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EBSCO Legal Collection, EBSCO Legal Source, EMBASE, MEDLINE, Directory of Open Access Journals, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Legal Collection (EBSCO), Legal Source (EBSCO)
- Anahtar Kelimeler: Postoperative sore throat, double-lumen tube, TrachoSpray, anesthesiology, thoracic surgery
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Postoperative sore throat (POST) is an distressing complication following endotracheal intubation, particularly with double-lumen tube (DLT) intubation. Study evaluated the effects of two local anesthetic techniques on hemodynamic responses and POST in DLT-intubated patients. Methods: A randomized controlled study was conducted with 60 patients scheduled for elective thoracic surgery. Participants were randomized into three groups: TrachoSpray group (2 mL of 10% lidocaine), Manual spray group (10% lidocaine) and, Control group (0.9% saline). Hemodynamic parameters, including systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP), were monitored preoperatively, intraoperatively, and postoperatively. POST was assessed using a visual analog scale at 2, 6, 12, and 24 h post-extubation. Results: Both lidocaine groups demonstrated significant reductions in SBP, DBP, and MAP at key time points compared to control group. Post-extubation, MAP was significantly higher in TrachoSpray group than lidocaine group (p = 0.04). No statistically significant differences in POST scores were observed between groups. Conclusions: TrachoSpray device and manual lidocaine spray improved hemodynamic stability in DLT-intubated patients; however, neither method resulted in a significant reduction in POST scores. Further research is needed to confirm these hemodynamic benefits and to explore potential effects on long-term outcomes.