Developing a New Collagen Peptide Serum Containing Gold Nanoparticles for Cosmetic Purposes


Kalay Ş.

Journal of Research in Pharmacy, cilt.27, sa.6, ss.2210-2217, 2023 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 6
  • Basım Tarihi: 2023
  • Doi Numarası: 10.29228/jrp.511
  • Dergi Adı: Journal of Research in Pharmacy
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.2210-2217
  • Anahtar Kelimeler: gold nanoparticles, collagen, cosmetic formulations, nanoparticle synthesis, skincare innovation
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

The reducing property of collagen was employed for the synthesis of gold nanoparticles (AuNPs) without the use of any toxic chemicals. The morphology of the resulting AuNPs-collagen particles appeared in spherical and triangular nanoprisms with sizes ranging from 30-60 nm, as observed in TEM results. Increasing the synthesis temperature led to the growth of AuNPs. Surface-enhanced Raman Spectroscopy studies revealed that amide I and carboxylic acid group vibrations indicated collagen binding to the Au surface through these groups. The AuNPs-collagen nanocomposite was tested for its antimicrobial properties against eight different microorganisms and it exhibited antibacterial properties solely against the Gordonia rubripertincta bacterium.