Successful off-label use of recombinant factor VIIa and coil embolization in an adolescent with massive hemoptysis due to invasive pulmonary aspergillosis İnvaziv pulmoner aspergillozise bağlı masif hemoptizi görülen adölesan bir hastada, endikasyon dışı rekombinan faktör VIIa’nın ve coil emobolizasyonunun başarılı kullanımı
Turkish Journal of Hematology, cilt.32, sa.1, ss.73-76, 2015 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 1
- Basım Tarihi: 2015
- Doi Numarası: 10.4274/tjh.2014.0347
- Dergi Adı: Turkish Journal of Hematology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.73-76
- Anahtar Kelimeler: Invasive pulmonary aspergillosis, Recombinant factor VIIa, Coil embolization, Children, Acute leukemia
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Invasive fungal infections have turned out to be a significant cause of morbidity and mortality in pediatric patients with malignant disorders. Massive hemoptysis, a rare complication of invasive pulmonary aspergillosis, may threaten the lives of patients, usually during the resolution of neutropenia. In this report, we describe a patient with massive hemoptysis due to invasive pulmonary aspergillosis whose bleeding was controlled successfully with off-label use of recombinant factor VIIa and subsequent coil embolization of the right pulmonary artery.