Does the teicoplanin skin test predict IgE-mediated hypersensitivity?
Allergologie Select, cilt.10, ss.98-100, 2026 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10
- Basım Tarihi: 2026
- Doi Numarası: 10.5414/alx02632e
- Dergi Adı: Allergologie Select
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.98-100
- Anahtar Kelimeler: IgE-mediated hypersensitivity, teicoplanin, skin prick test, intradermal test
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Various delayed-type hypersensitivity reactions have been reported following teicoplanin administration, including drug rash with eosinophilia and systemic symptoms (DRESS syndrome), and acute generalized exanthematous pustulosis (AGEP). Until recently, IgE-mediated hypersensitivity reactions to teicoplanin were considered to be rare. However, reports of such reactions have increased in recent years. These case reports also suggest that teicoplanin skin testing can predict IgE-mediated hypersensitivity reactions. In the present case, teicoplanin skin prick and intradermal tests were negative, yet an immediate skin reaction occurred during provocation. eosinophilia and systemic symptoms) syn-drome, and AGEP (acute generalized exanthematous pustulosis) [2, 3]. IgE-mediated hypersensitivity reactions to teicoplanin were considered rare until recently. However, case reports of IgE-mediated hypersensitivity to teicoplanin have been increasing in recent years [3, 4, 5]. These case reports also suggest that teicoplanin skin testing can predict IgE-mediated hypersensitivity reactions [4, 5]. The present case is a case in which teicoplanin skin prick and intradermal tests were negative but an early allergic reaction developed during provocation.