Inappropriate use of potent topical glucocorticoids in infants
Journal of Pediatric Endocrinology and Metabolism, cilt.20, sa.2, ss.219-225, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 2
- Basım Tarihi: 2007
- Doi Numarası: 10.1515/jpem.2007.20.2.219
- Dergi Adı: Journal of Pediatric Endocrinology and Metabolism
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.219-225
- Anahtar Kelimeler: Adrenal insufficiency, Cushing's syndrome, Glucocorticoids, Iatrogenic disease, Liver steatosis, Obesity, Topical administration
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Topical therapy with glucocorticoids (GCs) is used commonly in chronic dermatoses. Side effects are less common compared to systemic use; however, newer potent preparations may have serious side effects. A potential danger is their inappropriate use. Three infants who developed iatrogenic Cushing's syndrome and prolonged adrenal suppression in the course of GC therapy for simple diaper dermatitis are described. One patient also developed steatohepatitis which is uncommon with local GCs. © Freund Publishing House Ltd.