Isolated periorbital edema associated with naproxen: A case report


Onat S. S., ÖZİŞLER Z., Tasoglu O.

Asian Journal of Pharmaceutical Research and Health Care, cilt.6, sa.1, ss.23-25, 2014 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 1
  • Basım Tarihi: 2014
  • Dergi Adı: Asian Journal of Pharmaceutical Research and Health Care
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.23-25
  • Anahtar Kelimeler: Naproxen, periorbital edema
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs), resulting in urticaria and angioedema, is being observed with increasing frequency partly due to the large size of the exposed (at risk) population. Prevalence rates range from 0.1- 0.3%. Facial angioedema constitutes the most common form of clinical presentation, and one-third of the patients show a mixed clinical pattern of cutaneous (urticaria and/or angioedema) and respiratory symptoms which include upper respiratory tract edema, rhinorrhea, cough, breathlessness and tearing. But to the best of our knowledge there is no isolated periorbital edema reported to date due to naproxen in the literature. In this report, a 62-year-old woman who developed reversible bilateral periorbital edema after naproxen ingestion was presented. The periorbital edema due to NSAIDs was discussed.