Lupus myocarditis mimicking peripartum cardiomyopathy: A diagnostic challenge and successful clinical management


Dalkılıç Y. E., Doğan F. M., Soysal B., Ata E. B., YILMAZ S.

Modern Rheumatology Case Reports, cilt.10, sa.2, 2026 (ESCI, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 2
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1093/mrcr/rxag069
  • Dergi Adı: Modern Rheumatology Case Reports
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Anahtar Kelimeler: Lupus myocarditis, perinatal medicine, peripartum cardiomyopathy, SLE and pregnancy, systemic lupus erythematosus
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Lupus myocarditis and peripartum cardiomyopathy can both present with acute heart failure symptoms during the peripartum period, leading to diagnostic uncertainty. Accurate and timely recognition of lupus myocarditis is crucial due to its therapeutic implications and high mortality risk if misdiagnosed. This case report presents a 34-year-old female patient with systemic lupus erythematosus who presented to the emergency department 1 week postpartum with palpitations. In the presence of cardiac enzymes and a low ejection fraction on echocardiography, the patient was initially diagnosed with peripartum cardiomyopathy and subsequently accepted as lupus myocarditis due to clinical and laboratory findings suggestive of high systemic lupus erythematosus disease activity. The patient showed clinical improvement after pulse steroid and intravenous immunoglobulin therapy.